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Home About Traditions &＃038; History Careers at YCU Academics Undergraduate Study School of International Liberal Arts School of Economics and Business Administration School of Science School of Data Science School of Medicine School of Medicine: Medical Course School of Medicine: Nursing Course Graduate Study Graduate School of Urban Social and Cultural Studies Graduate School of International Management Graduate School of Nanobioscience Graduate School of Nanobioscience: Department of Materials System Science Graduate School of Nanobioscience: Department of Life and Environmental System Science Graduate School of Data Science Graduate School of Data Science: Department of Data Science Graduate School of Data Science: Department of Health Data Science Graduate School of Medical Life Science Graduate School of Medicine Graduate School of Medicine: Department of Medicine Graduate School of Medicine: Department of Nursing Non-Degree Programs Exchange Program International Clinical Clerkship Research-Only Career Development Support Admissions Research Advanced Medical Research Center Kihara Institute for Biological Research Life at YCU Kanazawa-Hakkei Campus Life Fukuura Campus Life Living in Yokohama Clubs &＃038; Societies Health &＃038; Wellness Global International Affairs Office Exchange Program Partner Institutions Global Cooperation Institute for Sustainable Cities (GCI) 日本語 NewsHome News Filter by Categories Tags Authors Show all AllAcademicsAMRCEmergencyFeaturedGlobalHomeResearchwids Allambassador lectureAMRCchemistrycoronavirusCOVID-19covid19datascienceemergency informationHealth Data ScienceHealth-MediacscKihara Institute for Biological Researchnanobioscienceokurayamasars-cov-2school of medicinescienceSentankenTsurumiwidsycumed AllYCU PR OfficeEditorYCU Global 2019-06-28Lubiprostone as a potential therapeutic agent to improve intestinal permeability and prevent the development of atherosclerosis in apolipoprotein E-deficient miceThe interaction between atherosclerosis and commensal microbes through leaky gut syndrome (LGS), which is characterized by impaired intestinal permeability and the introduction of undesired pathogens into the body, has not been fully elucidated. Our aim was to investigate the potential role of a ClC-2 chloride channel activator, lubiprostone, which is reported to have beneficial effects on LGS, in the development of atherosclerosis in apolipoprotein E–deficient (ApoE-/-) mice.Do you like it? Read more2019-06-10Comprehensive analysis of coding variants highlights genetic complexity in developmental and epileptic encephalopathyAlthough there are many known Mendelian genes linked to epileptic or developmental and epileptic encephalopathy (EE/DEE), its genetic architecture is not fully explained. Here, we address this incompleteness by analyzing exomes of 743 EE/DEE cases and 2366 controls. We observe that damaging ultra-rare variants (dURVs) unique to an individual are significantly overrepresented in EE/DEE, both in known EE/DEE genes and the other non-EE/DEE genes.Do you like it? Read more2019-06-09Okurayama International Forum 2019On June 29th, 2019, the ninth Okurayama International Student Forum was successfully held at Okurayama Memorial Hall in Yokohama. About 30 Japanese students from Yokohama City University, Tokyo Institute of Technology and Keio University had a cordial and friendly communication with students from Harvard University.Do you like it? Read more2019-05-14Genetic inhibition of CRMP2 phosphorylation at serine 522 promotes axonal regeneration after optic nerve injuryAxonal degeneration occurs in various neurological diseases and traumatic nerve injury, and axonal regeneration is restricted by inhibitory factors in the central nervous system. Cyclin-dependent kinase 5 and glycogen synthase kinase 3β (GSK3β) are activated by one of those inhibitors, and collapsin response mediator protein 2 (CRMP2) is phosphorylated by both kinases. We previously developed a CRMP2 knock-in (CRMP2 KI) mouse line, in which CRMP2 phosphorylation at Ser 522 is inhibited.Do you like it? Read more Prev page123456789101112131415161718192021222324252627282930313233343536373839404142434445464748495051525354555657585960616263646566676869Next page Search ✕ Latest newsActivity of MEXT Scholarship Alumni After Returning to Their Home Country2024-04-25Intraoperative Integrated Diagnostic System for Malignant Central Nervous System Tumors2023-11-21 Research Research News Advanced Medical Research Center Kihara Institute for Biological Research Researcher Database Global International Affairs Office International Student Support Exchange Program Partner Institutions Global Cooperation Institute for Sustainable Cities (GCI) GCI: Overview GCI: Activities International Academic Consortium for Sustainable Cities (IACSC) Living in Yokohama Admissions 22-2 Seto, Kanazawa-ku, Yokohama, Kanagawa 236-0027 Japan Undergraduate Schools International Liberal Arts Economics and Business Administration Science Data Science Medicine Graduate Schools Urban Social and Cultural Studies International Management Nanobioscience Medical Life Science Medicine  Data Science Admissions Undergraduate Graduate Non-Degree Programs Research Advanced Medical Research Center Kihara Institute for Biological Research Research Database Hospitals Yokohama City University Hospital Yokohama City University Medical Center Life at YCU Campus Life Living in Yokohama Clubs & Societies Health & Wellness Global International Affairs Office Global Cooperation Institute for Sustainable Cities Exchange Programs Partner Institutions NewsActivity of MEXT Scholarship Alumni After Returning to Their Home Country2024-04-25Simplifying the Estimation of Volatile Organic Compounds Emitted From Wildfires2023-10-26Event Report: The 14th IACSC International Symposium/General Assembly2023-10-10 © 2021 Yokohama City University. 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